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select follow-up compounds  (Tocris)


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    Structured Review

    Tocris select follow-up compounds
    Select Follow Up Compounds, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/select+follow-up+compounds/Tocriscreen+2%2E0+Mini/pm21050030-43-1-10
    Average 90 stars, based on 1 article reviews
    select follow-up compounds - by Bioz Stars, 2026-10
    90/100 stars

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    Article Title: Development and validation of a cell-based assay for the nuclear receptor retinoid-related orphan receptor gamma.
    Article Snippet: The nuclear receptor retinoid-related orphan receptor gamma (RORg) has become an attractive target for drug discovery due to its important role in the development and differentiation of Th17 cells, a subset of T cells that produce interleukin-17 and are involved in the pathogenesis of human inflammatory and autoimmune diseases.. To facilitate the drug discovery efforts in this area, we have developed a cellular assay for screening for RORg inverse agonists.. We stably engineered a tetracycline-inducible Gal4 DNA-binding domain/RORg ligand-binding domain fusion protein into an upstream activation sequence driven-betalactamase reporter gene cell line.



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    90
    Tocris select follow-up compounds
    Select Follow Up Compounds, supplied by Tocris, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/select+follow-up+compounds/Tocriscreen+2%2E0+Mini/pm21050030-43-1-10
    Average 90 stars, based on 1 article reviews
    select follow-up compounds - by Bioz Stars, 2026-10
    90/100 stars
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